Protein quantitation
Immunological assays
HPLC and UPLC-based assays for related substances and charged variants
Process residuals
Aggregate analysis by SEC and DLS
Process related impurities such as Host cell protein and Host cell DNA
Electrophoresis including Capillary electrophoresis and imaged capillary electrophoresis
Glycoform analysis including monosaccharide composition, glycan structure, glycosylation site determination by peptide maps, LC-MS/MS and NP-HPLC
Peptide mass fingerprinting and amino acid sequencing
Impurity characterization