Kashiv is aiming at developing new molecule entities either via de novo approach or via repurposing of known molecule for targeting various
therapeutic areas including Oncology, Pain, Parkinson, COVID 19 etc.
Kashiv
has an excellent blend of computational medicinal chemists capable
to design and modulate lead molecule via pharmacophore based scaffold
hopping by conducting systematic in silico testing focused library building for
in vitro in vivo screening
Kashiv
has an excellent team of pharmacologists clinicians for devising
appropriate animal model and clinical pathway to guide the project for IND
filing till conducting clinical trials using appropriate CRO/CMOs
NCE library generation
Drug synthesis
Lead optimization
Molecular docking
Supporting NCE synthesis (HPLC, LC-MS, NMR) Bioanalytical Activities-Multimode Plate Reader, FACS and LC-MS/MS, HR-MS based analysis
ADME Screening
Bioassays
Cell & molecular biology
Novel target validation
In-vivo DMPK
Safety pharmacology
Efficacy studies
Toxicology studies
Specialty Segment
Complex Injectables
Peptide Formulations
Innovative Drug Delivery
First-in-human studies
Dose ranging & dose finding
studies
Efficacy & Safety
studies in patients
Regulatory Strategy
Pre-IND to NDA filing
Agency communications
& liaison
Inhouse lawyers & IP
counsels for protecting
the innovations by
building network of patents